{"id":2900,"date":"2026-08-21T12:52:10","date_gmt":"2026-08-21T10:52:10","guid":{"rendered":"https:\/\/peptelia.com\/tb-500-2\/"},"modified":"2026-10-12T09:42:52","modified_gmt":"2026-10-12T07:42:52","slug":"tb-500","status":"publish","type":"page","link":"https:\/\/peptelia.com\/en\/library\/tb-500\/","title":{"rendered":"TB-500 (Thymosin Beta-4 Fragment)"},"content":{"rendered":"

TB-500 is the designation commonly used in the research field for a synthetically produced peptide derived structurally from the endogenous protein thymosin beta-4. Thymosin beta-4 is a small protein of 43 amino acids detectable in almost all mammalian tissue types, described in cell biology above all as an actin-binding molecule. TB-500 is usually classified as a synthetic fragment or derivative of this protein and is produced exclusively for laboratory purposes.<\/p>\n

Unlike the native protein, TB-500 does not come from a biological source but is produced by solid-phase peptide synthesis and subsequently purified chromatographically. In the scientific literature the substance appears predominantly in the context of preclinical investigations in cell cultures and animal models. No approval as a medicine exists; TB-500 is classified exclusively as reference and research material.<\/p>\n

Profile<\/h2>\n

Molecule type:<\/strong> synthetic peptide, derived from thymosin beta-4<\/p>\n

Reference protein:<\/strong> thymosin beta-4 (43 amino acids)<\/p>\n

Production:<\/strong> solid-phase peptide synthesis, purification by HPLC<\/p>\n

Research classification:<\/strong> research chemical, Research Use Only (RUO)<\/p>\n

Research context<\/h2>\n

Thymosin beta-4 and fragments derived from it have been studied in basic cell biology research for decades. Central to this is the interaction with G-actin, a fundamental building block of the cytoskeleton: published work addresses how the molecule influences actin dynamics and related processes such as cell migration and cell morphology in vitro.<\/p>\n

Beyond this, TB-500 is examined in preclinical models in connection with tissue regeneration and repair processes, for instance in cell culture and animal studies. This work is basic research: it describes observations under controlled laboratory conditions as described in the preclinical literature, and these findings do not support conclusions about effects in humans. Pept\u00e9lia reports such research fields solely for the scientific classification of the molecule.<\/p>\n

Quality criteria for laboratory procurement<\/h2>\n

The quality of the starting material is decisive for reproducible research results. Every batch should be accompanied by a certificate of analysis (COA) documenting identity and purity. Customary components are an HPLC analysis to determine chromatographic purity and mass spectrometry to confirm the molecular mass.<\/p>\n

Complete batch documentation matters just as much: every delivery unit should be assigned to a unique batch number so that analytical results remain traceable. Lyophilised peptides are stored cool, dry and protected from light; for long-term storage in the laboratory, keeping them in the freezer is customary.<\/p>\n

Frequently asked questions<\/h2>\n

Is TB-500 legal?<\/h3>\n

TB-500 is not an approved medicine and must not be supplied or used for application in humans or animals. As a research chemical, however, the peptide can lawfully be obtained for scientific laboratory purposes. Buyers are themselves responsible for complying with the regulations applicable in their country for handling research materials.<\/p>\n

What should be checked on the COA?<\/h3>\n

An informative COA names the batch number, the purity determined by HPLC and, where identity is critical to the research question, the molecular mass confirmed by mass spectrometry. It is important that the certificate can be unambiguously assigned to the batch supplied and names the testing lab and the method used.<\/p>\n

How is TB-500 stored?<\/h3>\n

As a lyophilised solid, TB-500 is kept dry, protected from light and cool; for longer storage periods, freezer storage is advisable in the laboratory context. Repeated temperature fluctuations should be avoided, since they can generally impair the stability of peptides.<\/p>\n

Available at Pept\u00e9lia<\/h2>\n

Pept\u00e9lia carries TB-500 as documented research material with a batch-specific certificate of analysis (COA). All available variants can be found in the TB-500 category – lyophilised in a vial (10 and 15 mg), as a capsule formulation and in the combined research set.<\/p>\n

TB-500 and BPC-157 are frequently named together in the literature, although structurally they have nothing to do with one another. How the two peptides differ, why they appear in the same model classes and in which formats they are available is set out in the comparison of BPC-157 and TB-500.<\/p>\n

Important notice<\/h2>\n

All substances offered by Pept\u00e9lia are intended exclusively for scientific use in the laboratory (Research Use Only). They are not medicines, not food supplements and not cosmetics. Use in humans or animals, as well as any diagnostic or therapeutic use, is expressly excluded.<\/strong><\/p>\n

For research use only. Not for use in or on the human body.<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

TB-500 is the designation commonly used in the research field for a synthetically produced peptide derived structurally from the endogenous protein thymosin beta-4. Thymosin beta-4 is a small protein of […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":3101,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_templately_pack_id":"","_templately_imported_at":"","_templately_source":"","_templately_import_session_id":"","footnotes":""},"class_list":["post-2900","page","type-page","status-publish","hentry"],"yoast_head":"\nTB-500 (Thymosin Beta-4 Fragment) \u2013 Profile | Pept\u00e9lia<\/title>\n<meta name=\"description\" content=\"TB-500 research profile: the thymosin beta-4 fragment, the mechanisms examined in regenerative research and the vial sizes available. Research use only.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/peptelia.com\/en\/library\/tb-500\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"TB-500 (Thymosin Beta-4 Fragment) \u2013 Profile | Pept\u00e9lia\" \/>\n<meta property=\"og:description\" content=\"TB-500 research profile: the thymosin beta-4 fragment, the mechanisms examined in regenerative research and the vial sizes available. Research use only.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/peptelia.com\/en\/library\/tb-500\/\" \/>\n<meta property=\"og:site_name\" content=\"Pept\u00e9lia\" \/>\n<meta property=\"article:modified_time\" content=\"2026-10-12T07:42:52+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/peptelia.com\/wp-content\/uploads\/2026\/08\/tb-500-10mg.png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/library\\\/tb-500\\\/\",\"url\":\"https:\\\/\\\/peptelia.com\\\/en\\\/library\\\/tb-500\\\/\",\"name\":\"TB-500 (Thymosin Beta-4 Fragment) \u2013 Profile | Pept\u00e9lia\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/#website\"},\"datePublished\":\"2026-08-21T10:52:10+00:00\",\"dateModified\":\"2026-10-12T07:42:52+00:00\",\"description\":\"TB-500 research profile: the thymosin beta-4 fragment, the mechanisms examined in regenerative research and the vial sizes available. Research use only.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/library\\\/tb-500\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/peptelia.com\\\/en\\\/library\\\/tb-500\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/library\\\/tb-500\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Start\",\"item\":\"https:\\\/\\\/peptelia.com\\\/en\\\/peptelia\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Library\",\"item\":\"https:\\\/\\\/peptelia.com\\\/en\\\/library\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"TB-500 (Thymosin Beta-4 Fragment)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/peptelia.com\\\/en\\\/\",\"name\":\"Pept\u00e9lia\",\"description\":\"Peptide GLP-1, GLP-2 & GLP-3 \u2013 COA-verifiziert\",\"publisher\":{\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/#organization\"},\"alternateName\":\"Peptelia Peptides\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/peptelia.com\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/#organization\",\"name\":\"Pept\u00e9lia\",\"url\":\"https:\\\/\\\/peptelia.com\\\/en\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/peptelia.com\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/peptelia-logo-blue-r.png.webp\",\"contentUrl\":\"https:\\\/\\\/peptelia.com\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/peptelia-logo-blue-r.png.webp\",\"width\":300,\"height\":254,\"caption\":\"Pept\u00e9lia\"},\"image\":{\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"TB-500 (Thymosin Beta-4 Fragment) \u2013 Profile | Pept\u00e9lia","description":"TB-500 research profile: the thymosin beta-4 fragment, the mechanisms examined in regenerative research and the vial sizes available. Research use only.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/peptelia.com\/en\/library\/tb-500\/","og_locale":"en_US","og_type":"article","og_title":"TB-500 (Thymosin Beta-4 Fragment) \u2013 Profile | Pept\u00e9lia","og_description":"TB-500 research profile: the thymosin beta-4 fragment, the mechanisms examined in regenerative research and the vial sizes available. Research use only.","og_url":"https:\/\/peptelia.com\/en\/library\/tb-500\/","og_site_name":"Pept\u00e9lia","article_modified_time":"2026-10-12T07:42:52+00:00","og_image":[{"url":"https:\/\/peptelia.com\/wp-content\/uploads\/2026\/08\/tb-500-10mg.png","type":"","width":"","height":""}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/peptelia.com\/en\/library\/tb-500\/","url":"https:\/\/peptelia.com\/en\/library\/tb-500\/","name":"TB-500 (Thymosin Beta-4 Fragment) \u2013 Profile | Pept\u00e9lia","isPartOf":{"@id":"https:\/\/peptelia.com\/en\/#website"},"datePublished":"2026-08-21T10:52:10+00:00","dateModified":"2026-10-12T07:42:52+00:00","description":"TB-500 research profile: the thymosin beta-4 fragment, the mechanisms examined in regenerative research and the vial sizes available. Research use only.","breadcrumb":{"@id":"https:\/\/peptelia.com\/en\/library\/tb-500\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/peptelia.com\/en\/library\/tb-500\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/peptelia.com\/en\/library\/tb-500\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Start","item":"https:\/\/peptelia.com\/en\/peptelia\/"},{"@type":"ListItem","position":2,"name":"Library","item":"https:\/\/peptelia.com\/en\/library\/"},{"@type":"ListItem","position":3,"name":"TB-500 (Thymosin Beta-4 Fragment)"}]},{"@type":"WebSite","@id":"https:\/\/peptelia.com\/en\/#website","url":"https:\/\/peptelia.com\/en\/","name":"Pept\u00e9lia","description":"Peptide GLP-1, GLP-2 & GLP-3 \u2013 COA-verifiziert","publisher":{"@id":"https:\/\/peptelia.com\/en\/#organization"},"alternateName":"Peptelia Peptides","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/peptelia.com\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/peptelia.com\/en\/#organization","name":"Pept\u00e9lia","url":"https:\/\/peptelia.com\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/peptelia.com\/en\/#\/schema\/logo\/image\/","url":"https:\/\/peptelia.com\/wp-content\/uploads\/2026\/09\/peptelia-logo-blue-r.png.webp","contentUrl":"https:\/\/peptelia.com\/wp-content\/uploads\/2026\/09\/peptelia-logo-blue-r.png.webp","width":300,"height":254,"caption":"Pept\u00e9lia"},"image":{"@id":"https:\/\/peptelia.com\/en\/#\/schema\/logo\/image\/"}}]}},"_hostinger_reach_plugin_has_subscription_block":false,"_hostinger_reach_plugin_is_elementor":false,"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/peptelia.com\/en\/wp-json\/wp\/v2\/pages\/2900","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/peptelia.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/peptelia.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/peptelia.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/peptelia.com\/en\/wp-json\/wp\/v2\/comments?post=2900"}],"version-history":[{"count":5,"href":"https:\/\/peptelia.com\/en\/wp-json\/wp\/v2\/pages\/2900\/revisions"}],"predecessor-version":[{"id":4185,"href":"https:\/\/peptelia.com\/en\/wp-json\/wp\/v2\/pages\/2900\/revisions\/4185"}],"up":[{"embeddable":true,"href":"https:\/\/peptelia.com\/en\/wp-json\/wp\/v2\/pages\/3101"}],"wp:attachment":[{"href":"https:\/\/peptelia.com\/en\/wp-json\/wp\/v2\/media?parent=2900"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}