{"id":231,"count":1,"description":"<strong>Buy ACE-031<\/strong> \u2013 ACE-031 is a recombinant fusion protein combining the extracellular domain of activin receptor type IIB (ActRIIB) with the Fc fragment of a human IgG1. Acting as a soluble receptor decoy, the construct binds ligands of the TGF-beta superfamily, among them myostatin (GDF-8), activin A and GDF-11, before they reach membrane-bound receptors. In basic research ACE-031 therefore serves as a model substance for mapping ligand selectivity across the ActRIIB axis, for interrupting the downstream SMAD2\/3 cascade in myoblast and fibroblast cultures, and for separating the contribution of individual ligands in cell and animal models. The literature also describes how the Fc portion extends residence time in model systems compared with soluble receptor fragments lacking Fc, and what cross-reactivity toward related type II receptors occurs. Structurally, ACE-031 stands clearly apart from the short-chain peptides of this section, which act on pituitary G protein-coupled receptors. Pept\u00e9lia supplies the substance as a lyophilisate in a vial, with reconstitution and storage details on the product page; related working materials are grouped under the parent section Growth Factor Research. Each batch is tested in-house by HPLC and UV\/Vis spectroscopy; the batch-specific certificate of analysis is available before purchase. <strong>For research use only. Not for use in or on the human body.<\/strong>","link":"https:\/\/peptelia.com\/en\/product-category\/growth-factor-research\/ace-031\/","name":"ACE-031","slug":"ace-031","taxonomy":"product_cat","parent":232,"meta":[],"menu_order":0,"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Buy ACE-031 \u2013 Research Protein with COA | Pept\u00e9lia<\/title>\n<meta name=\"description\" content=\"ACE-031 (soluble ActRIIB fusion protein) for research on myostatin signalling. Batch-specific COA \u2013 for laboratory and research use only.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/peptelia.com\/en\/product-category\/growth-factor-research\/ace-031\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Buy ACE-031 \u2013 Research Protein with COA | Pept\u00e9lia\" \/>\n<meta property=\"og:description\" content=\"ACE-031 (soluble ActRIIB fusion protein) for research on myostatin signalling. Batch-specific COA \u2013 for laboratory and research use only.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/peptelia.com\/en\/product-category\/growth-factor-research\/ace-031\/\" \/>\n<meta property=\"og:site_name\" content=\"Pept\u00e9lia\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"CollectionPage\",\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/product-category\\\/growth-factor-research\\\/ace-031\\\/\",\"url\":\"https:\\\/\\\/peptelia.com\\\/en\\\/product-category\\\/growth-factor-research\\\/ace-031\\\/\",\"name\":\"Buy ACE-031 \u2013 Research Protein with COA | Pept\u00e9lia\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/#website\"},\"description\":\"ACE-031 (soluble ActRIIB fusion protein) for research on myostatin signalling. Batch-specific COA \u2013 for laboratory and research use only.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/product-category\\\/growth-factor-research\\\/ace-031\\\/#breadcrumb\"},\"inLanguage\":\"en-US\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/product-category\\\/growth-factor-research\\\/ace-031\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Start\",\"item\":\"https:\\\/\\\/peptelia.com\\\/en\\\/peptelia\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Growth Factor Research\",\"item\":\"https:\\\/\\\/peptelia.com\\\/en\\\/product-category\\\/growth-factor-research\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"ACE-031\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/peptelia.com\\\/en\\\/\",\"name\":\"Pept\u00e9lia\",\"description\":\"Peptide GLP-1, GLP-2 &amp; GLP-3 \u2013 COA-verifiziert\",\"publisher\":{\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/#organization\"},\"alternateName\":\"Peptelia Peptides\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/peptelia.com\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/#organization\",\"name\":\"Pept\u00e9lia\",\"url\":\"https:\\\/\\\/peptelia.com\\\/en\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/peptelia.com\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/peptelia-logo-blue-r.png.webp\",\"contentUrl\":\"https:\\\/\\\/peptelia.com\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/peptelia-logo-blue-r.png.webp\",\"width\":300,\"height\":254,\"caption\":\"Pept\u00e9lia\"},\"image\":{\"@id\":\"https:\\\/\\\/peptelia.com\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Buy ACE-031 \u2013 Research Protein with COA | Pept\u00e9lia","description":"ACE-031 (soluble ActRIIB fusion protein) for research on myostatin signalling. Batch-specific COA \u2013 for laboratory and research use only.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/peptelia.com\/en\/product-category\/growth-factor-research\/ace-031\/","og_locale":"en_US","og_type":"article","og_title":"Buy ACE-031 \u2013 Research Protein with COA | Pept\u00e9lia","og_description":"ACE-031 (soluble ActRIIB fusion protein) for research on myostatin signalling. Batch-specific COA \u2013 for laboratory and research use only.","og_url":"https:\/\/peptelia.com\/en\/product-category\/growth-factor-research\/ace-031\/","og_site_name":"Pept\u00e9lia","twitter_card":"summary_large_image","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"CollectionPage","@id":"https:\/\/peptelia.com\/en\/product-category\/growth-factor-research\/ace-031\/","url":"https:\/\/peptelia.com\/en\/product-category\/growth-factor-research\/ace-031\/","name":"Buy ACE-031 \u2013 Research Protein with COA | Pept\u00e9lia","isPartOf":{"@id":"https:\/\/peptelia.com\/en\/#website"},"description":"ACE-031 (soluble ActRIIB fusion protein) for research on myostatin signalling. Batch-specific COA \u2013 for laboratory and research use only.","breadcrumb":{"@id":"https:\/\/peptelia.com\/en\/product-category\/growth-factor-research\/ace-031\/#breadcrumb"},"inLanguage":"en-US"},{"@type":"BreadcrumbList","@id":"https:\/\/peptelia.com\/en\/product-category\/growth-factor-research\/ace-031\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Start","item":"https:\/\/peptelia.com\/en\/peptelia\/"},{"@type":"ListItem","position":2,"name":"Growth Factor Research","item":"https:\/\/peptelia.com\/en\/product-category\/growth-factor-research\/"},{"@type":"ListItem","position":3,"name":"ACE-031"}]},{"@type":"WebSite","@id":"https:\/\/peptelia.com\/en\/#website","url":"https:\/\/peptelia.com\/en\/","name":"Pept\u00e9lia","description":"Peptide GLP-1, GLP-2 &amp; GLP-3 \u2013 COA-verifiziert","publisher":{"@id":"https:\/\/peptelia.com\/en\/#organization"},"alternateName":"Peptelia Peptides","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/peptelia.com\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/peptelia.com\/en\/#organization","name":"Pept\u00e9lia","url":"https:\/\/peptelia.com\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/peptelia.com\/en\/#\/schema\/logo\/image\/","url":"https:\/\/peptelia.com\/wp-content\/uploads\/2026\/09\/peptelia-logo-blue-r.png.webp","contentUrl":"https:\/\/peptelia.com\/wp-content\/uploads\/2026\/09\/peptelia-logo-blue-r.png.webp","width":300,"height":254,"caption":"Pept\u00e9lia"},"image":{"@id":"https:\/\/peptelia.com\/en\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/peptelia.com\/en\/wp-json\/wp\/v2\/product_cat\/231","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/peptelia.com\/en\/wp-json\/wp\/v2\/product_cat"}],"about":[{"href":"https:\/\/peptelia.com\/en\/wp-json\/wp\/v2\/taxonomies\/product_cat"}],"up":[{"embeddable":true,"href":"https:\/\/peptelia.com\/en\/wp-json\/wp\/v2\/product_cat\/232"}],"wp:post_type":[{"href":"https:\/\/peptelia.com\/en\/wp-json\/wp\/v2\/product?product_cat=231"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}