{"id":234,"count":1,"description":"<strong>Buy AOD-9604<\/strong> \u2013 AOD-9604 is a synthetic peptide analogue corresponding to the C-terminal section 176\u2013191 of human growth hormone, carrying an additional stabilising tyrosine residue at the N-terminus. The fragment lacks the domains essential for receptor binding of full-length hGH, which is why the literature discusses it as a model for receptor-independent effects of the hormone molecule. In basic research AOD-9604 is used to characterise lipolytic signalling pathways in isolated adipocytes, in particular the role of \u03b23-adrenergic signalling and hormone-sensitive lipase. Further questions concern separating fragment activity from the IGF-1-mediated axis, and work in cartilage and chondrocyte models describing matrix-related markers. Instructive is the structural comparison with the native 176\u2013191 fragment: the extra tyrosine residue improves handling and analytical detectability, while the disulfide bridge between the two cysteines fixes the loop conformation and makes the substance sensitive to reducing buffer conditions. Pept\u00e9lia supplies AOD-9604 as a lyophilisate in a vial, with reconstitution and storage details on the product page. Thematically related sequences are reachable through the parent category Metabolic Research. Each batch is tested in-house by HPLC and UV\/Vis spectroscopy; the batch-specific certificate of analysis is available before purchase. <strong>For research use only. Not for use in or on the human body.<\/strong>","link":"https:\/\/peptelia.com\/en\/product-category\/metabolic-research\/aod-9604\/","name":"AOD-9604","slug":"aod-9604","taxonomy":"product_cat","parent":208,"meta":{"_templately_pack_id":"","_templately_imported_at":"","_templately_source":"","_templately_import_session_id":""},"menu_order":0,"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Buy AOD-9604 \u2013 Research Peptide with COA | Pept\u00e9lia<\/title>\n<meta name=\"description\" content=\"AOD-9604, a C-terminal hGH fragment analogue, for metabolic research. 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