{"id":236,"count":2,"description":"<strong>Buy CJC-1295<\/strong> \u2013 CJC-1295 is a synthetic analogue of growth hormone-releasing hormone, derived from the first 29 amino acids of human GHRH. Four targeted amino acid substitutions in the N-terminal section reduce cleavage by dipeptidyl peptidase IV. The variant with Drug Affinity Complex additionally carries a maleimide group that couples covalently to serum albumin in model systems, whereas the form without DAC \u2013 usually listed in the literature as Modified GRF (1-29) \u2013 lacks this binding site. Work in pituitary cell cultures and animal models examines how the GHRH receptor, a class B GPCR, signals through the cAMP\/PKA pathway, how pulsatile versus sustained receptor occupancy modulates the somatotropic axis, and whether receptor desensitisation occurs. The side-by-side comparison of both variants makes the compound a useful tool for separating half-life concepts in model systems from receptor activation itself \u2013 an aspect that cannot be represented in the same way with ghrelin receptor agonists. Pept\u00e9lia supplies it as a lyophilisate in a vial, with reconstitution and storage details on the product page; complementary compound classes are listed under Growth Factor Research. Each batch is tested in-house by HPLC and UV\/Vis spectroscopy; the batch-specific certificate of analysis is available before purchase. <strong>For research use only. Not for use in or on the human body.<\/strong>","link":"https:\/\/peptelia.com\/en\/product-category\/growth-factor-research\/cjc-1295\/","name":"CJC-1295","slug":"cjc-1295","taxonomy":"product_cat","parent":232,"meta":[],"menu_order":0,"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Buy CJC-1295 \u2013 Research Peptide with COA | Pept\u00e9lia<\/title>\n<meta name=\"description\" content=\"CJC-1295 as a GHRH-analogue research peptide with batch-specific COA and HPLC-tested purity. 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