Buy VIP

Buy VIP – Vasoactive Intestinal Peptide is a 28-amino-acid neuropeptide belonging to the secretin-glucagon family that binds receptors of the VPAC1 and VPAC2 type. First isolated from small intestinal tissue, it was later also detected in the central and peripheral nervous system as well as in immune cells – one reason why it sits at the interface of neurobiology and immunology in research. In preclinical models VIP is used as a model compound for questions concerning inflammation-associated signalling pathways, the regulation of circadian rhythmicity in the suprachiasmatic nucleus, and the modulation of T-cell responses in cell culture. As a linear peptide of this length, VIP is sensitive to peptidases and to surface adsorption; working solutions are therefore usually prepared fresh in the literature and repeated freeze-thaw cycles are avoided. Peptélia supplies VIP as a lyophilisate in a 5 mg vial, with reconstitution and storage details on the product page. Related compounds from the same research field can be found under Immunology Research. Each batch is tested in-house by HPLC and UV/Vis spectroscopy, and the batch-specific certificate of analysis is viewable before purchase. For research use only. Not for use in or on the human body.