Buy NAD+

Buy NAD+ – Nicotinamide adenine dinucleotide is a dinucleotide of nicotinamide mononucleotide and adenosine monophosphate joined by a pyrophosphate bridge. As the central coenzyme of energy metabolism it alternates between oxidised NAD+ and reduced NADH, as the nicotinamide ring accepts or releases a hydride ion. In basic research NAD+ serves as a model substance for quantifying the NAD+/NADH ratio in cell lysates and isolated mitochondria; studies also examine its consumption as a substrate by ADP-ribosylating enzymes such as sirtuins and PARPs, and its regeneration from nicotinamide by salvage pathway enzymes. The kinetics of NAD+-dependent dehydrogenases are likewise described at length. Analytically useful is the clear distinction between the redox forms: only NADH shows the characteristic absorption at 340 nm, so enzymatic assays can be followed photometrically. The disodium salt is hygroscopic and of limited stability in alkaline solution; it differs from the precursors NMN and NR in its complete dinucleotide structure. At Peptélia, NAD+ is available as a lyophilisate in a vial, with reconstitution and storage details on the product page, classified within Skin & Cell Research. Each batch is tested in-house by HPLC and UV/Vis spectroscopy, and the batch certificate of analysis is viewable before purchase. For research use only. Not for use in or on the human body.