Buy Melanotan

Buy Melanotan – The Melanotan Research category covers the synthetic analogues of alpha-melanocyte-stimulating hormone, abbreviated MT-1 and MT-2. MT-1 is a linear tridecapeptide derived from native alpha-MSH by substitution at two amino acid positions; MT-2 is a shortened cyclic heptapeptide whose ring is closed by a lactam bridge between an aspartic acid and a lysine residue. Both address the G-protein-coupled melanocortin receptors MC1R to MC5R. In basic research they serve as model substances of receptor biology: studies examine binding affinity and selectivity at individual receptor subtypes, downstream cAMP formation in receptor-bearing cell lines, and the regulation of tyrosinase activity and melanin formation in melanocyte and melanoma cell cultures. Structurally, the comparison of the two peptides is instructive: cyclisation of MT-2 restricts conformational freedom and markedly increases resistance to enzymatic degradation relative to the linear template, which makes it a frequently used reference in structure-activity studies. At Peptélia the peptides of this category are available as lyophilisates in vials, with reconstitution and storage details on the product page, classified within Skin & Cell Research. Each batch is tested in-house by HPLC and UV/Vis spectroscopy, and the batch certificate of analysis is viewable before purchase. For research use only. Not for use in or on the human body.